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Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery

New antibiotics are needed to combat the growing problem of resistant bacterial infections. An attractive avenue toward the discovery of such next-generation therapies is to identify novel inhibitors of clinically validated targets, like cell wall biogenesis. We have therefore developed a pathway-di...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Buss, Jackson A., Baidin, Vadim, Welsh, Michael A., Flores-Kim, Josué, Cho, Hongbaek, Wood, B. McKay, Uehara, Tsuyoshi, Walker, Suzanne, Kahne, Daniel, Bernhardt, Thomas G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325226/
https://ncbi.nlm.nih.gov/pubmed/30323039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01530-18
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