Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery

New antibiotics are needed to combat the growing problem of resistant bacterial infections. An attractive avenue toward the discovery of such next-generation therapies is to identify novel inhibitors of clinically validated targets, like cell wall biogenesis. We have therefore developed a pathway-di...

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Buss, Jackson A., Baidin, Vadim, Welsh, Michael A., Flores-Kim, Josué, Cho, Hongbaek, Wood, B. McKay, Uehara, Tsuyoshi, Walker, Suzanne, Kahne, Daniel, Bernhardt, Thomas G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2018
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Mechanisms of Action: Physiological Effects
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325226/
https://ncbi.nlm.nih.gov/pubmed/30323039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01530-18
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