Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery

New antibiotics are needed to combat the growing problem of resistant bacterial infections. An attractive avenue toward the discovery of such next-generation therapies is to identify novel inhibitors of clinically validated targets, like cell wall biogenesis. We have therefore developed a pathway-di...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Buss, Jackson A., Baidin, Vadim, Welsh, Michael A., Flores-Kim, Josué, Cho, Hongbaek, Wood, B. McKay, Uehara, Tsuyoshi, Walker, Suzanne, Kahne, Daniel, Bernhardt, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325226/
https://ncbi.nlm.nih.gov/pubmed/30323039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01530-18
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