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A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery

Cell elongation in rod-shaped bacteria is mediated by the Rod system, a conserved morphogenic complex that spatially controls cell wall assembly by the glycan polymerase RodA and crosslinking enzyme PBP2. Using Escherichia coli as a model system, we identified a PBP2 variant that promotes Rod system...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Rohs, Patricia D. A., Buss, Jackson, Sim, Sue I., Squyres, Georgia R., Srisuknimit, Veerasak, Smith, Mandy, Cho, Hongbaek, Sjodt, Megan, Kruse, Andrew C., Garner, Ethan C., Walker, Suzanne, Kahne, Daniel E., Bernhardt, Thomas G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207328/
https://ncbi.nlm.nih.gov/pubmed/30335755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007726
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