A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery

Cell elongation in rod-shaped bacteria is mediated by the Rod system, a conserved morphogenic complex that spatially controls cell wall assembly by the glycan polymerase RodA and crosslinking enzyme PBP2. Using Escherichia coli as a model system, we identified a PBP2 variant that promotes Rod system...

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Detalles Bibliográficos
Publicado en:PLoS Genet
Main Authors: Rohs, Patricia D. A., Buss, Jackson, Sim, Sue I., Squyres, Georgia R., Srisuknimit, Veerasak, Smith, Mandy, Cho, Hongbaek, Sjodt, Megan, Kruse, Andrew C., Garner, Ethan C., Walker, Suzanne, Kahne, Daniel E., Bernhardt, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207328/
https://ncbi.nlm.nih.gov/pubmed/30335755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007726
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