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Pathway-Directed Screen for Inhibitors of the Bacterial Cell Elongation Machinery

New antibiotics are needed to combat the growing problem of resistant bacterial infections. An attractive avenue toward the discovery of such next-generation therapies is to identify novel inhibitors of clinically validated targets, like cell wall biogenesis. We have therefore developed a pathway-di...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Buss, Jackson A., Baidin, Vadim, Welsh, Michael A., Flores-Kim, Josué, Cho, Hongbaek, Wood, B. McKay, Uehara, Tsuyoshi, Walker, Suzanne, Kahne, Daniel, Bernhardt, Thomas G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325226/
https://ncbi.nlm.nih.gov/pubmed/30323039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01530-18
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