Use of Translational Pharmacokinetic/Pharmacodynamic Infection Models To Understand the Impact of Neutropenia on the Efficacy of Tedizolid Phosphate

Tedizolid phosphate, the prodrug of the active antibiotic tedizolid, is an oxazolidinone for the treatment of acute bacterial skin and skin structure infections. Studies in a mouse thigh infection model demonstrated that tedizolid has improved potency and pharmacokinetics/pharmacodynamics (PK/PD) co...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Xiao, Jianying, Gill, Charles, Liang, Lianzhu, Liu, Jenny, Wu, Jin, Feng, Hwa-Ping, Flanagan, Shawn, Tan, Christopher, Flattery, Amy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2018
Gaiak:
Pharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325206/
https://ncbi.nlm.nih.gov/pubmed/30373794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00822-18
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