Tedizolid Population Pharmacokinetics, Exposure Response, and Target Attainment

Tedizolid phosphate is a novel antibacterial prodrug that is rapidly and extensively converted to its active moiety, tedizolid. We developed a population pharmacokinetics (PK) model for tedizolid using pooled data from seven densely and sparsely sampled clinical trials evaluating oral and intravenou...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Flanagan, S., Passarell, J., Lu, Q., Fiedler-Kelly, J., Ludwig, E., Prokocimer, P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249359/
https://ncbi.nlm.nih.gov/pubmed/25136028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03423-14
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