Exposure‐safety and efficacy response relationships and population pharmacokinetics of eslicarbazepine acetate

OBJECTIVES: Eslicarbazepine acetate (ESL) is a once‐daily (QD) oral antiepileptic drug (AED) for focal‐onset seizures (FOS). Pharmacokinetic (PK) and pharmacodynamic (PD) models were developed to assess dose selection, identify significant AED drug interactions, and quantitate relationships between...

詳細記述

保存先:
書誌詳細
出版年:Acta Neurol Scand
主要な著者: Gidal, B. E., Jacobson, M. P., Ben‐Menachem, E., Carreño, M., Blum, D., Soares‐da‐Silva, P., Falcão, A., Rocha, F., Moreira, J., Grinnell, T., Ludwig, E., Fiedler‐Kelly, J., Passarell, J., Sunkaraneni, S.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2018
主題:
Original Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099471/
https://ncbi.nlm.nih.gov/pubmed/29732549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ane.12950
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