Modeling and simulations to support dose selection for eslicarbazepine acetate therapy in pediatric patients with partial-onset seizures

Modeling and simulations were used to support body weight-based dose selection for eslicarbazepine acetate (ESL) in pediatric subjects aged 4–17 years with partial-onset seizures. A one-compartment pediatric population pharmacokinetic model with formulation-specific first-order absorption, first-ord...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Pharmacokinet Pharmacodyn
Egile Nagusiak: Sunkaraneni, Soujanya, Ludwig, Elizabeth, Fiedler-Kelly, Jill, Hopkins, Seth, Galluppi, Gerald, Blum, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer US 2018
Gaiak:
Original Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061080/
https://ncbi.nlm.nih.gov/pubmed/29948795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-018-9596-7
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