Azole Resistance Reduces Susceptibility to the Tetrazole Antifungal VT-1161

Tetrazole antifungals designed to target fungal lanosterol 14α-demethylase (LDM) appear to be effective against a range of fungal pathogens. In addition, a crystal structure of the catalytic domain of Candida albicans LDM in complex with the tetrazole VT-1161 has been obtained. We have addressed con...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Monk, Brian C., Keniya, Mikhail V., Sabherwal, Manya, Wilson, Rajni K., Graham, Danyon O., Hassan, Harith F., Chen, Danni, Tyndall, Joel D. A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325177/
https://ncbi.nlm.nih.gov/pubmed/30397057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02114-18
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker