Mutations in the MAB_2299c TetR Regulator Confer Cross-Resistance to Clofazimine and Bedaquiline in Mycobacterium abscessus

New therapeutic approaches are needed against Mycobacterium abscessus, a respiratory mycobacterial pathogen that evades efforts to successfully treat infected patients. Clofazimine and bedaquiline, two drugs used for the treatment of multidrug-resistant tuberculosis, are being considered as alternat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Richard, Matthias, Gutiérrez, Ana Victoria, Viljoen, Albertus, Rodriguez-Rincon, Daniela, Roquet-Baneres, Françoise, Blaise, Mickael, Everall, Isobel, Parkhill, Julian, Floto, R. Andres, Kremer, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325171/
https://ncbi.nlm.nih.gov/pubmed/30323043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01316-18
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados