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The TetR Family Transcription Factor MAB_2299c Regulates the Expression of Two Distinct MmpS-MmpL Efflux Pumps Involved in Cross-Resistance to Clofazimine and Bedaquiline in Mycobacterium abscessus

Mycobacterium abscessus is a human pathogen responsible for severe respiratory infections, particularly in patients with underlying lung disorders. Notorious for being highly resistant to most antimicrobials, new therapeutic approaches are needed to successfully treat M. abscessus-infected patients....

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Gutiérrez, Ana Victoria, Richard, Matthias, Roquet-Banères, Françoise, Viljoen, Albertus, Kremer, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761555/
https://ncbi.nlm.nih.gov/pubmed/31332077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01000-19
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