Mutations in the transcriptional regulator MAB_2885 confer tedizolid and linezolid resistance through the MmpS-MmpL efflux pump MAB_2302-MAB_2303 in Mycobacterium abscessus.

Mycobacterium abscessus (MAB) is a clinically significant multidrug-resistant (MDR) pathogen, particularly implicated in pulmonary infections among cystic fibrosis (CF) patients. Tedizolid (TZD), an oxazolidinone-class antibacterial drug, has been recommended as an alternative treatment for MAB-infe...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Huiyun Zhang, Shiyong Wang, Yu Zhang, Wenya Hua, Siran Lin, Xinchang Chen, Tao Xu, Jiazhen Chen, Wenhong Zhang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2025-05-01
Sarja:PLoS Pathogens
Linkit:https://doi.org/10.1371/journal.ppat.1013190
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia