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The TetR Family Transcription Factor MAB_2299c Regulates the Expression of Two Distinct MmpS-MmpL Efflux Pumps Involved in Cross-Resistance to Clofazimine and Bedaquiline in Mycobacterium abscessus

Mycobacterium abscessus is a human pathogen responsible for severe respiratory infections, particularly in patients with underlying lung disorders. Notorious for being highly resistant to most antimicrobials, new therapeutic approaches are needed to successfully treat M. abscessus-infected patients....

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Gutiérrez, Ana Victoria, Richard, Matthias, Roquet-Banères, Françoise, Viljoen, Albertus, Kremer, Laurent
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761555/
https://ncbi.nlm.nih.gov/pubmed/31332077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01000-19
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