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Verapamil Improves the Activity of Bedaquiline against Mycobacterium abscessus In Vitro and in Macrophages

Due to intrinsic multidrug resistance, pulmonary infections with Mycobacterium abscessus are extremely difficult to treat. Previously, we demonstrated that bedaquiline is highly effective against Mycobacterium abscessus both in vitro and in vivo. Here, we report that verapamil improves the efficacy...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Viljoen, Albertus, Raynaud, Clément, Johansen, Matt D., Roquet-Banères, Françoise, Herrmann, Jean-Louis, Daher, Wassim, Kremer, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709475/
https://ncbi.nlm.nih.gov/pubmed/31209005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00705-19
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