Synergistic Interactions of Indole-2-Carboxamides and β-Lactam Antibiotics against Mycobacterium abscessus

New drugs or therapeutic combinations are urgently needed against Mycobacterium abscessus. Previously, we demonstrated the potent activity of indole-2-carboxamides 6 and 12 against M. abscessus. We show here that these compounds act synergistically with imipenem and cefoxitin in vitro and increase t...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Raynaud, Clément, Daher, Wassim, Roquet-Banères, Françoise, Johansen, Matt D., Stec, Jozef, Onajole, Oluseye K., Ordway, Diane, Kozikowski, Alan P., Kremer, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179587/
https://ncbi.nlm.nih.gov/pubmed/32041716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02548-19
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