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Spatial Dynamics of Chromosome Translocations in Living Cells

Chromosome translocations are a hallmark of cancer cells. We have developed an experimental system to visualize the formation of translocations in living cells and apply it to characterize the spatial and dynamic properties of translocation formation. We demonstrate that translocations form within h...

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Détails bibliographiques
Publié dans:Science
Auteurs principaux: Roukos, Vassilis, Voss, Ty C., Schmidt, Christine K., Lee, Seungtaek, Wangsa, Darawalee, Misteli, Tom
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324928/
https://ncbi.nlm.nih.gov/pubmed/23929981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1237150
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