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Spatial Dynamics of Chromosome Translocations in Living Cells

Chromosome translocations are a hallmark of cancer cells. We have developed an experimental system to visualize the formation of translocations in living cells and apply it to characterize the spatial and dynamic properties of translocation formation. We demonstrate that translocations form within h...

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Publicat a:Science
Autors principals: Roukos, Vassilis, Voss, Ty C., Schmidt, Christine K., Lee, Seungtaek, Wangsa, Darawalee, Misteli, Tom
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324928/
https://ncbi.nlm.nih.gov/pubmed/23929981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1237150
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