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Generation of cell-based systems to visualize chromosome damage and translocations in living cells
Traditional methods for the generation of DNA damage are not well suited for the observation of spatiotemporal aspects of damaged chromosomal loci. We describe a protocol for the derivation of a cellular system to induce and to visualize chromosome damage at specific sites of the mammalian genome in...
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| Опубликовано в: : | Nat Protoc |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6391998/ https://ncbi.nlm.nih.gov/pubmed/25255091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.167 |
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