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Spatial Dynamics of Chromosome Translocations in Living Cells

Chromosome translocations are a hallmark of cancer cells. We have developed an experimental system to visualize the formation of translocations in living cells and apply it to characterize the spatial and dynamic properties of translocation formation. We demonstrate that translocations form within h...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Roukos, Vassilis, Voss, Ty C., Schmidt, Christine K., Lee, Seungtaek, Wangsa, Darawalee, Misteli, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324928/
https://ncbi.nlm.nih.gov/pubmed/23929981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1237150
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