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Spatial Dynamics of Chromosome Translocations in Living Cells

Chromosome translocations are a hallmark of cancer cells. We have developed an experimental system to visualize the formation of translocations in living cells and apply it to characterize the spatial and dynamic properties of translocation formation. We demonstrate that translocations form within h...

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發表在:Science
Main Authors: Roukos, Vassilis, Voss, Ty C., Schmidt, Christine K., Lee, Seungtaek, Wangsa, Darawalee, Misteli, Tom
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324928/
https://ncbi.nlm.nih.gov/pubmed/23929981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1237150
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