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The cellular etiology of chromosome translocations

Chromosome translocations are the most severe form of genome defect. Translocations represent the end product of a series of cellular mistakes and they form after cells suffer multiple DNA double strand breaks (DSBs), which evade the surveillance mechanisms that usually eliminate them. Rather than b...

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Bibliografiske detaljer
Main Authors: Roukos, Vassilis, Burman, Bharat, Misteli, Tom
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688675/
https://ncbi.nlm.nih.gov/pubmed/23498663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2013.02.015
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