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The biogenesis of chromosome translocations

Chromosome translocations are catastrophic genomic events and often play key roles in tumorigenesis. Yet the biogenesis of chromosome translocations is remarkably poorly understood. Recent work has delineated several distinct mechanistic steps in the formation of translocations, and it has become ap...

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Publicat a:Nat Cell Biol
Autors principals: Roukos, Vassilis, Misteli, Tom
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337718/
https://ncbi.nlm.nih.gov/pubmed/24691255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2941
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