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The biogenesis of chromosome translocations

Chromosome translocations are catastrophic genomic events and often play key roles in tumorigenesis. Yet the biogenesis of chromosome translocations is remarkably poorly understood. Recent work has delineated several distinct mechanistic steps in the formation of translocations, and it has become ap...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Roukos, Vassilis, Misteli, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337718/
https://ncbi.nlm.nih.gov/pubmed/24691255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2941
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