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In vivo assembly and large-scale purification of a GPCR - Gα fusion with Gβγ, and characterization of the active complex
G protein coupled receptors (GPCRs) are central players in recognizing a variety of stimuli to mediate diverse cellular responses. This myriad of functions is accomplished by their modular interactions with downstream intracellular transducers, such as heterotrimeric G proteins and arrestins. Assemb...
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| Vydáno v: | PLoS One |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6324789/ https://ncbi.nlm.nih.gov/pubmed/30620756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210131 |
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