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In vivo assembly and large-scale purification of a GPCR - Gα fusion with Gβγ, and characterization of the active complex

G protein coupled receptors (GPCRs) are central players in recognizing a variety of stimuli to mediate diverse cellular responses. This myriad of functions is accomplished by their modular interactions with downstream intracellular transducers, such as heterotrimeric G proteins and arrestins. Assemb...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Kumar, Abhinav, Plückthun, Andreas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324789/
https://ncbi.nlm.nih.gov/pubmed/30620756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210131
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