Interaction of G-Protein βγ Complex with Chromatin Modulates GPCR-Dependent Gene Regulation

Heterotrimeric G-protein signal transduction initiated by G-protein-coupled receptors (GPCRs) in the plasma membrane is thought to propagate through protein-protein interactions of subunits, Gα and Gβγ in the cytosol. In this study, we show novel nuclear functions of Gβγ through demonstrating intera...

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Detalhes bibliográficos
Main Authors: Bhatnagar, Anushree, Unal, Hamiyet, Jagannathan, Rajaganapathi, Kaveti, Suma, Duan, Zhong-Hui, Yong, Sandro, Vasanji, Amit, Kinter, Michael, Desnoyer, Russell, Karnik, Sadashiva S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541368/
https://ncbi.nlm.nih.gov/pubmed/23326349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052689
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