Benzolactam-related compounds promote apoptosis of HIV-infected human cells via protein kinase C–induced HIV latency reversal

Latency-reversing agents (LRAs) are considered a potential strategy for curing cells of HIV-1 infection. Certain protein kinase C (PKC) activators have been previously reported to be LRAs because they can reverse HIV latency. In the present study, we examined the activities of a panel of benzolactam...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Matsuda, Kouki, Kobayakawa, Takuya, Tsuchiya, Kiyoto, Hattori, Shin-ichiro, Nomura, Wataru, Gatanaga, Hiroyuki, Yoshimura, Kazuhisa, Oka, Shinichi, Endo, Yasuyuki, Tamamura, Hirokazu, Mitsuya, Hiroaki, Maeda, Kenji
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322896/
https://ncbi.nlm.nih.gov/pubmed/30413535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005798
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