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Replacement of Lys-300 with a glutamine in the NhaA Na(+)/H(+) antiporter of Escherichia coli yields a functional electrogenic transporter
Much of the research on Na(+)/H(+) exchange has been done in prokaryotic models, mainly on the NhaA Na(+)/H(+)-exchanger from Escherichia coli (EcNhaA). Two conserved aspartate residues, Asp-163 and Asp-164, are essential for transport and are candidates for possible binding sites for the two H(+) t...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6322889/ https://ncbi.nlm.nih.gov/pubmed/30409911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004903 |
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