NhaA Na(+)/H(+) Antiporter Mutants That Hardly React to the Membrane Potential

pH and Na(+) homeostasis in all cells requires Na(+)/H(+) antiporters. The crystal structure, obtained at pH 4, of NhaA, the main antiporter of Escherichia coli, has provided general insights into an antiporter mechanism and its unique pH regulation. Here, we describe a general method to select vari...

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Main Authors: Alkoby, Dudu, Rimon, Abraham, Burdak, Maral, Patino-Ruiz, Miyer, Călinescu, Octavian, Fendler, Klaus, Padan, Etana
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974702/
https://ncbi.nlm.nih.gov/pubmed/24699187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093200
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