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NhaA Na(+)/H(+) Antiporter Mutants That Hardly React to the Membrane Potential

pH and Na(+) homeostasis in all cells requires Na(+)/H(+) antiporters. The crystal structure, obtained at pH 4, of NhaA, the main antiporter of Escherichia coli, has provided general insights into an antiporter mechanism and its unique pH regulation. Here, we describe a general method to select vari...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Alkoby, Dudu, Rimon, Abraham, Burdak, Maral, Patino-Ruiz, Miyer, Călinescu, Octavian, Fendler, Klaus, Padan, Etana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974702/
https://ncbi.nlm.nih.gov/pubmed/24699187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093200
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