Replacement of Lys-300 with a glutamine in the NhaA Na(+)/H(+) antiporter of Escherichia coli yields a functional electrogenic transporter

Much of the research on Na(+)/H(+) exchange has been done in prokaryotic models, mainly on the NhaA Na(+)/H(+)-exchanger from Escherichia coli (EcNhaA). Two conserved aspartate residues, Asp-163 and Asp-164, are essential for transport and are candidates for possible binding sites for the two H(+) t...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Patiño-Ruiz, Miyer, Dwivedi, Manish, Călinescu, Octavian, Karabel, Mehmet, Padan, Etana, Fendler, Klaus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2019
Konular:
Molecular Biophysics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322889/
https://ncbi.nlm.nih.gov/pubmed/30409911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004903
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