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The Influence of Protonation States on the Dynamics of the NhaA Antiporter from Escherichia coli

The crystal structure of NhaA Na(+)/H(+) antiporter of Escherichia coli has provided a basis to explore the mechanism of Na(+) and H(+) exchange and its regulation by pH. However, the dynamics and nature of the pH-induced changes in the proteins remained unknown. Using molecular mechanics methods, w...

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Detalhes bibliográficos
Main Authors: Olkhova, Elena, Padan, Etana, Michel, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868976/
https://ncbi.nlm.nih.gov/pubmed/17350999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.098269
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