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Mepazine Inhibits RANK-Induced Osteoclastogenesis Independent of Its MALT1 Inhibitory Function

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) is an intracellular cysteine protease (paracaspase) that plays an integral role in innate and adaptive immunity. The phenothiazine mepazine has been shown to inhibit the proteolytic activity of MALT1 and is frequently used to...

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Bibliografische gegevens
Gepubliceerd in:Molecules
Hoofdauteurs: Meloni, Laura, Verstrepen, Lynn, Kreike, Marja, Staal, Jens, Driege, Yasmine, Afonina, Inna S., Beyaert, Rudi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320945/
https://ncbi.nlm.nih.gov/pubmed/30513612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123144
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