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Inhibitory Effect of Naphthoquinone-Tryptophan Hybrid towards Aggregation of PAP f39 Semen Amyloid

PAP(248–286), a 39 amino acid peptide fragment, derived from the prostatic acid phosphatase secreted in human semen, forms amyloid fibrils and facilitates the attachment of retroviruses to host cells that results in the enhancement of viral infection. Therefore, the inhibition of amyloid formation b...

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Publicado en:Molecules
Autores principales: Viswanathan, Guru KrishnaKumar, Mohapatra, Satabdee, Paul, Ashim, Arad, Elad, Jelinek, Raz, Gazit, Ehud, Segal, Daniel
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320874/
https://ncbi.nlm.nih.gov/pubmed/30544943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123279
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