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Naphthoquinone Tryptophan Hybrids: A Promising Small Molecule Scaffold for Mitigating Aggregation of Amyloidogenic Proteins and Peptides

A current challenge faced by researchers is the lack of disease-modifying therapeutics for amyloid formation that is associated with several human diseases. Although the monomeric proteins or peptides involved in various amyloidogenic diseases do not have amino acid sequence homology, there appears...

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Dades bibliogràfiques
Publicat a:Front Cell Dev Biol
Autors principals: Viswanathan, Guru KrishnaKumar, Paul, Ashim, Gazit, Ehud, Segal, Daniel
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6843079/
https://ncbi.nlm.nih.gov/pubmed/31750300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00242
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