Inhibitory Effect of Naphthoquinone-Tryptophan Hybrid towards Aggregation of PAP f39 Semen Amyloid

PAP(248–286), a 39 amino acid peptide fragment, derived from the prostatic acid phosphatase secreted in human semen, forms amyloid fibrils and facilitates the attachment of retroviruses to host cells that results in the enhancement of viral infection. Therefore, the inhibition of amyloid formation b...

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Vydáno v:Molecules
Hlavní autoři: Viswanathan, Guru KrishnaKumar, Mohapatra, Satabdee, Paul, Ashim, Arad, Elad, Jelinek, Raz, Gazit, Ehud, Segal, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320874/
https://ncbi.nlm.nih.gov/pubmed/30544943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123279
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