The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model

Recent clinical studies have demonstrated the protective effect of xanthine oxidase (XO) inhibitors against chronic kidney diseases, although the underlying molecular mechanisms remain unclear. However, to date, neither clinical nor basic research has been carried out to elucidate the efficacy of XO...

詳細記述

保存先:
書誌詳細
出版年:Int J Mol Sci
主要な著者: Inoue, Masa-Ki, Yamamotoya, Takeshi, Nakatsu, Yusuke, Ueda, Koji, Inoue, Yuki, Matsunaga, Yasuka, Sakoda, Hideyuki, Fujishiro, Midori, Ono, Hiraku, Morii, Kenichi, Sasaki, Kensuke, Masaki, Takao, Suzuki, Yusuke, Asano, Tomoichiro, Kushiyama, Akifumi
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320819/
https://ncbi.nlm.nih.gov/pubmed/30544662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19123967
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