Thermal Stability and Epitope Integrity of a Lyophilized Ricin Toxin Subunit Vaccine

Biodefense vaccine are destined to be stockpiled for periods of time and deployed in the event of a public health emergency. In this report, we compared the potency of liquid and lyophilized (thermostabilized) formulations of a candidate ricin toxin subunit vaccine, RiVax, adsorbed to aluminum salts...

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Bibliographic Details
Published in:Vaccine
Main Authors: Westfall, Jennifer, Yates, Jennifer L, Van Slyke, Greta, Ehrbar, Dylan, Measey, Thomas, Straube, Richard, Donini, Oreola, Mantis, Nicholas J.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6320669/
https://ncbi.nlm.nih.gov/pubmed/30172637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2018.08.059
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