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A Supercluster of Neutralizing Epitopes at the Interface of Ricin’s Enzymatic (RTA) and Binding (RTB) Subunits

As part of an effort to engineer ricin antitoxins and immunotherapies, we previously produced and characterized a collection of phage-displayed, heavy chain-only antibodies (V(H)Hs) from alpacas that had been immunized with ricin antigens. In our initial screens, we identified nine V(H)Hs directed a...

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Podrobná bibliografie
Vydáno v:Toxins (Basel)
Hlavní autoři: Poon, Amanda Y., Vance, David J., Rong, Yinghui, Ehrbar, Dylan, Mantis, Nicholas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744098/
https://ncbi.nlm.nih.gov/pubmed/29168727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9120378
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