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A Supercluster of Neutralizing Epitopes at the Interface of Ricin’s Enzymatic (RTA) and Binding (RTB) Subunits

As part of an effort to engineer ricin antitoxins and immunotherapies, we previously produced and characterized a collection of phage-displayed, heavy chain-only antibodies (V(H)Hs) from alpacas that had been immunized with ricin antigens. In our initial screens, we identified nine V(H)Hs directed a...

詳細記述

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書誌詳細
出版年:Toxins (Basel)
主要な著者: Poon, Amanda Y., Vance, David J., Rong, Yinghui, Ehrbar, Dylan, Mantis, Nicholas J.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744098/
https://ncbi.nlm.nih.gov/pubmed/29168727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9120378
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