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A Supercluster of Neutralizing Epitopes at the Interface of Ricin’s Enzymatic (RTA) and Binding (RTB) Subunits

As part of an effort to engineer ricin antitoxins and immunotherapies, we previously produced and characterized a collection of phage-displayed, heavy chain-only antibodies (V(H)Hs) from alpacas that had been immunized with ricin antigens. In our initial screens, we identified nine V(H)Hs directed a...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Toxins (Basel)
Main Authors: Poon, Amanda Y., Vance, David J., Rong, Yinghui, Ehrbar, Dylan, Mantis, Nicholas J.
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744098/
https://ncbi.nlm.nih.gov/pubmed/29168727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9120378
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