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Sensitivity of Kupffer cells and liver sinusoidal endothelial cells to ricin toxin and ricin toxin–Ab complexes

Ricin toxin is a plant‐derived, ribosome‐inactivating protein that is rapidly cleared from circulation by Kupffer cells (KCs) and liver sinusoidal endothelial cells (LSECs)—with fatal consequences. Rather than being inactivated, ricin evades normal degradative pathways and kills both KCs and LSECs w...

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Dettagli Bibliografici
Pubblicato in:J Leukoc Biol
Autori principali: Mooney, Bridget, Torres‐Velez, Fernando J., Doering, Jennifer, Ehrbar, Dylan J., Mantis, Nicholas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008010/
https://ncbi.nlm.nih.gov/pubmed/31313388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4A0419-123R
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