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Sensitivity of Kupffer cells and liver sinusoidal endothelial cells to ricin toxin and ricin toxin–Ab complexes

Ricin toxin is a plant‐derived, ribosome‐inactivating protein that is rapidly cleared from circulation by Kupffer cells (KCs) and liver sinusoidal endothelial cells (LSECs)—with fatal consequences. Rather than being inactivated, ricin evades normal degradative pathways and kills both KCs and LSECs w...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Mooney, Bridget, Torres‐Velez, Fernando J., Doering, Jennifer, Ehrbar, Dylan J., Mantis, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008010/
https://ncbi.nlm.nih.gov/pubmed/31313388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4A0419-123R
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