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Sensitivity of Kupffer cells and liver sinusoidal endothelial cells to ricin toxin and ricin toxin–Ab complexes

Ricin toxin is a plant‐derived, ribosome‐inactivating protein that is rapidly cleared from circulation by Kupffer cells (KCs) and liver sinusoidal endothelial cells (LSECs)—with fatal consequences. Rather than being inactivated, ricin evades normal degradative pathways and kills both KCs and LSECs w...

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Detalles Bibliográficos
Publicado en:J Leukoc Biol
Main Authors: Mooney, Bridget, Torres‐Velez, Fernando J., Doering, Jennifer, Ehrbar, Dylan J., Mantis, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008010/
https://ncbi.nlm.nih.gov/pubmed/31313388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4A0419-123R
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