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Sensitivity of Kupffer cells and liver sinusoidal endothelial cells to ricin toxin and ricin toxin–Ab complexes

Ricin toxin is a plant‐derived, ribosome‐inactivating protein that is rapidly cleared from circulation by Kupffer cells (KCs) and liver sinusoidal endothelial cells (LSECs)—with fatal consequences. Rather than being inactivated, ricin evades normal degradative pathways and kills both KCs and LSECs w...

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Détails bibliographiques
Publié dans:J Leukoc Biol
Auteurs principaux: Mooney, Bridget, Torres‐Velez, Fernando J., Doering, Jennifer, Ehrbar, Dylan J., Mantis, Nicholas J.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008010/
https://ncbi.nlm.nih.gov/pubmed/31313388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4A0419-123R
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