Stabilization of a Recombinant Ricin Toxin A Subunit Vaccine through Lyophilization

Lyophilization was used to prepare dry, glassy solid vaccine formulations of recombinant ricin toxin A-chain containing suspensions of colloidal aluminum hydroxide adjuvant. Four lyophilized formulations were prepared by using combinations of rapid or slow cooling during lyophilization and one of tw...

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Detalhes bibliográficos
Main Authors: Hassett, Kimberly J., Cousins, Megan C., Rabia, Lilia A., Chadwick, Chrystal M., O’Hara, Joanne M., Nandi, Pradyot, Brey, Robert N., Mantis, Nicholas J., Carpenter, John F., Randolph, Theodore W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797224/
https://ncbi.nlm.nih.gov/pubmed/23583494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2013.03.029
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