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Comparative Efficacy of Two Leading Candidate Ricin Toxin A Subunit Vaccines in Mice
The two leading ricin toxin vaccine candidates, RVEc and RiVax, are recombinant derivatives of the toxin's 267-amino-acid enzymatic A chain (RTA). RVEc is truncated at the C terminus (residues 199 to 267) to improve protein thermostability, while RiVax has two point mutations (V76M and Y80A) th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3675979/ https://ncbi.nlm.nih.gov/pubmed/23515013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00098-13 |
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