Oncogenic BRAF(V600E) governs regulatory T cell recruitment during melanoma tumorigenesis

Regulatory T cells (Tregs) are critical mediators of immune suppression in established tumors, although little is known about their role in restraining immune surveillance during tumorigenesis. Here we employ an inducible autochthonous model of melanoma to investigate the earliest Treg and CD8 effec...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Shabaneh, Tamer B., Molodtsov, Aleksey K., Steinberg, Shannon M., Zhang, Peisheng, Torres, Gretel M., Mohamed, Gadisti A., Boni, Andrea, Curiel, Tyler J., Angeles, Christina V., Jo Turk, Mary
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319620/
https://ncbi.nlm.nih.gov/pubmed/30026331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0365
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