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BRAF-inhibition alleviates immune suppression in murine autochthonous melanoma

A growing body of evidence suggests that BRAF inhibitors, in addition to their acute tumor growth-inhibitory effects, can also promote immune responses to melanoma. The present studies aimed to define the immunologic basis of BRAF-inhibitor therapy using the Braf/Pten model of inducible, autochthono...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Immunol Res
Hauptverfasser: Steinberg, Shannon M., Zhang, Peisheng, Malik1, Brian T., Boni, Andrea, Shabaneh, Tamer B., Byrne, Katelyn T., Mullins, David W., Brinckerhoff, Constance E., Ernstoff, Marc S., Bosenberg, Marcus, Turk, Mary Jo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230697/
https://ncbi.nlm.nih.gov/pubmed/25183499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0074
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