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Oncogenic BRAF(V600E) governs regulatory T cell recruitment during melanoma tumorigenesis

Regulatory T cells (Tregs) are critical mediators of immune suppression in established tumors, although little is known about their role in restraining immune surveillance during tumorigenesis. Here we employ an inducible autochthonous model of melanoma to investigate the earliest Treg and CD8 effec...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Res
Hauptverfasser: Shabaneh, Tamer B., Molodtsov, Aleksey K., Steinberg, Shannon M., Zhang, Peisheng, Torres, Gretel M., Mohamed, Gadisti A., Boni, Andrea, Curiel, Tyler J., Angeles, Christina V., Jo Turk, Mary
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319620/
https://ncbi.nlm.nih.gov/pubmed/30026331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0365
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