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Oncogenic BRAF(V600E) Induces Clastogenesis and UVB Hypersensitivity

The oncogenic BRAF(V600E) mutation is common in melanomas as well as moles. The roles that this mutation plays in the early events in the development of melanoma are poorly understood. This study demonstrates that expression of BRAF(V600E) is not only clastogenic, but synergizes for clastogenesis ca...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Simpson, Dennis A., Lemonie, Nathalay, Morgan, David S., Gaddameedhi, Shobhan, Kaufmann, William K.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491700/
https://ncbi.nlm.nih.gov/pubmed/26091525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers7020825
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