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Oncogenic BRAF(V600E) Induces Clastogenesis and UVB Hypersensitivity

The oncogenic BRAF(V600E) mutation is common in melanomas as well as moles. The roles that this mutation plays in the early events in the development of melanoma are poorly understood. This study demonstrates that expression of BRAF(V600E) is not only clastogenic, but synergizes for clastogenesis ca...

詳細記述

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書誌詳細
出版年:Cancers (Basel)
主要な著者: Simpson, Dennis A., Lemonie, Nathalay, Morgan, David S., Gaddameedhi, Shobhan, Kaufmann, William K.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491700/
https://ncbi.nlm.nih.gov/pubmed/26091525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers7020825
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