BRAF V600E Inhibitor (Vemurafenib) for BRAF V600E Mutated Low Grade Gliomas

Low-grade gliomas (LGG) are the most common central nervous system tumors in children. Prognosis depends on complete surgical resection. For patients not amenable of gross total resection (GTR) new approaches are needed. The BRAF mutation V600E is critical for the pathogenesis of pediatric gliomas a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Oncol
Egile Nagusiak: Del Bufalo, Francesca, Ceglie, Giulia, Cacchione, Antonella, Alessi, Iside, Colafati, Giovanna Stefania, Carai, Andrea, Diomedi-Camassei, Francesca, De Billy, Emmanuel, Agolini, Emanuele, Mastronuzzi, Angela, Locatelli, Franco
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2018
Gaiak:
Oncology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6246660/
https://ncbi.nlm.nih.gov/pubmed/30488019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00526
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