Response of recurrent BRAFV600E mutated ganglioglioma to Vemurafenib as single agent

BACKGROUND: Ganglioglioma (GG) and pilocytic astrocytoma (PA) represent the most frequent low-grade gliomas (LGG) occurring in paediatric age. LGGs not amenable of complete resection (CR) represent a challenging subgroup where traditional treatments often fail. Activation of the MAP Kinase (MAPK) pa...

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Dades bibliogràfiques
Publicat a:J Transl Med
Autors principals: del Bufalo, Francesca, Carai, Andrea, Figà-Talamanca, Lorenzo, Pettorini, Benedetta, Mallucci, Conor, Giangaspero, Felice, Antonelli, Manila, Badiali, Manuela, Moi, Loredana, Bianco, Giuseppe, Cacchione, Antonella, Locatelli, Franco, Ferretti, Elisabetta, Mastronuzzi, Angela
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279809/
https://ncbi.nlm.nih.gov/pubmed/25524464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0356-1
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