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Polygenic Risk Score for Coronary Heart Disease Modifies the Elevated Risk by Cigarette Smoking for Disease Incidence

BACKGROUND: Coronary heart disease (CHD) is a multifactorial disease with both genetic and environmental components. Smoking is the most important modifiable risk factor for CHD. Our aim was to test whether the increased CHD incidence by smoking is modified by genetic predisposition to CHD. METHODS...

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書目詳細資料
發表在:Circ Genom Precis Med
Main Authors: Hindy, George, Wiberg, Frans, Almgren, Peter, Melander, Olle, Orho-Melander, Marju
格式: Artigo
語言:Inglês
出版: Lippincott Williams & Wilkins 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319562/
https://ncbi.nlm.nih.gov/pubmed/29874179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.117.001856
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