Phase I/II clinical trial of the targeted chemotherapeutic drug, folate-tubulysin, in dogs with naturally-occurring invasive urothelial carcinoma

PURPOSE: The purpose was to determine the safety and antitumor activity of a folate-tubulysin conjugate (EC0531) in a relevant preclinical animal model, dogs with naturally-occurring invasive urothelial carcinoma (iUC). Canine iUC is an aggressive cancer with high folate receptor (FR) expression sim...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Szigetvari, Nicholas M., Dhawan, Deepika, Ramos-Vara, José A., Leamon, Christopher P., Klein, Patrick J., Ruple, A. Audrey, Heng, Hock Gan, Pugh, Michael R., Rao, Satish, Vlahov, Iontcho R., Deshuillers, Pierre L., Low, Philip S., Fourez, Lindsey M., Cournoyer, Ashleigh M., Knapp, Deborah W.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319348/
https://ncbi.nlm.nih.gov/pubmed/30651934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26455
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados