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Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancer

There is growing evidence that molecular subtypes (e.g. luminal and basal subtypes) affect the prognosis and treatment response in patients with muscle invasive urinary bladder cancer (invasive urothelial carcinoma, iUC). Modeling these subtypes in pre-clinical animal studies is essential, but it is...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Dhawan, Deepika, Hahn, Noah M., Ramos-Vara, José A., Knapp, Deborah W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101404/
https://ncbi.nlm.nih.gov/pubmed/30089113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007571
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