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Lysosomal Sequestration Impairs the Activity of the Preclinical FGFR Inhibitor PD173074
Knowledge of intracellular pharmacokinetics of anticancer agents is imperative for understanding drug efficacy as well as intrinsic and acquired cellular resistance mechanisms. However, the factors driving subcellular drug distribution are complex and poorly understood. Here, we describe for the fir...
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| Publicado no: | Cells |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6315953/ https://ncbi.nlm.nih.gov/pubmed/30544798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7120259 |
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