The FGFR1 inhibitor PD173074 induces mesenchymal–epithelial transition through the transcription factor AP-1

BACKGROUND: Epithelial–mesenchymal transition (EMT) is a crucial process in cancer progression that provides cancer cells with the ability to escape from the primary focus, invade stromal tissues and migrate to distant regions. Cell lines that lack E-cadherin show increased tumorigenesis and metasta...

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Detalhes bibliográficos
Main Authors: Nguyen, P T, Tsunematsu, T, Yanagisawa, S, Kudo, Y, Miyauchi, M, Kamata, N, Takata, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798957/
https://ncbi.nlm.nih.gov/pubmed/24045665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.550
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